Pulmonary damage with gold or penicillamine.
نویسندگان
چکیده
منابع مشابه
Relationship of gold and penicillamine therapy to diffuse interstitial lung disease.
Seven cases of diffuse interstitial lung disease (DILD) are reported with an unequivocal temporal relationship between the development of the lung disease and treatment with gold (6 cases) and penicillamine (1 case). They were characterised clinically by the sudden onset of dyspnoea and crepitations and radiologically by diffuse bilateral pulmonary shadowing. Most showed evidence of hypersensit...
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We describe four men who had symptoms of acute mercury poisoning following exposure to mercury vapor. They were attempting home gold ore purification using a gold-mercury amalgam and sulfuric acid. Three of the four patients required treatment with penicillamine. The clinical and laboratory data are presented along with pulmonary function test results. Long-term follow-up of one patient indicat...
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Penicillamine is as effective as gold' when used as an antirheumatic drug.2 Side effects may occur, however, the best recognised being marrow suppression, the nephrotic syndrome, abnormalities of taste, rashes, and gastrointestinal disturbances. All are usually reversible on stopping treatment. Nevertheless, deaths have occurred, and recently three fatal cases of Goodpasture's syndrome were rep...
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Life-table analysis was applied to the records of 317 patients with rheumatoid arthritis (RA) treated with sulphasalazine (SAS), 201 treated with sodium aurothiomalate (gold), and 163 with penicillamine. They comprised all those treated in our department with these drugs between January 1973 and July 1984. Risks of treatment termination for all reasons were similar for each drug at five years (...
متن کاملPrediction of progressive joint damage in patients with rheumatoid arthritis receiving gold or D-penicillamine therapy.
Seventy two patients with classical or definite rheumatoid arthritis (RA) were randomly allocated to receive gold or D-penicillamine therapy (DPA) in a prospective study designed to evaluate whether it is possible to predict which patients will show radiological progression despite therapy. Forty five patients completed 12 months' treatment. There were no significant demographic or clinical dif...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 40 5 شماره
صفحات -
تاریخ انتشار 1981